Author

K. Pierce

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Organism:human· 2 Approach:statistical model· 2 Approach:deep learning· 1

Frequent Co-Authors

C. B. Clish· 2 shared A. Deik· 1 shared A. Panda· 1 shared A. Regev· 1 shared A. S. Fisch· 1 shared A. Schnell· 1 shared A. Wagner· 1 shared B. Gigliotti· 1 shared

Activity by Year

2020-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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2 shared papersMicrobiology

C. B. Clish

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Vaginal Lactobacillus fatty acid response mechanisms reveal a novel strategy for bacterial vaginosis treatment

M. Zhu, M. W. Frank, C. D. Radka, S. Jeanfavre, M. W. Tse, J. Avila Pacheco, K. Pierce, A. Deik, J. Xhu, S. Hussain, F. A. Hussain, N. Xulu, N. Khan, V. Pillay, K. L. Dong, , D. S. Kwon

This study identifies oleic acid as a compound that inhibits L. iners and promotes L. crispatus growth, offering a potential new treatment strategy for bacterial vaginosis.

bioRxiv · Dec 30, 2023 · PreprintMicrobiology

Effectors enabling adaptation to mitochondrial complex I loss in Hurthle cell carcinoma

R. K. Gopal, V. R. Vantaku, A. Panda, B. Reimer, S. Rath, T.-L. To, A. S. Fisch, M. Cetinbas, M. Livneh, M. J. Calcaterra, B. Gigliotti, K. Pierce, C. B. Clish, D. Dias-Santagata, P. M. Sadow, , V. Mootha

This study identifies molecular effectors in Hurthle cell carcinoma linked to mitochondrial complex I loss, highlighting lipid peroxide scavenging as a therapeutic vulnerability.

bioRxiv · Aug 16, 2022Cancer Biology

Metabolic and Epigenomic Regulation of Th17/Treg Balance by the Polyamine Pathway

C. Wang, A. Wagner, J. Fessler, J. Avila-Pacheco, J. Karminski, P. Thakore, S. Zaghouani, K. Pierce, L. Bod, A. Schnell, D. DeTomaso, N. Ron-Harel, M. Haigis, D. Puleston, E. Pearce, , V. Kuchroo

The paper identifies the polyamine pathway as a regulator of Th17/Treg balance, showing its impact on inflammation and T cell phenotype.

bioRxiv · Jan 23, 2020 · PreprintImmunology