Author

S.-A. E. Nicholas

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:mouse· 2 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1

Frequent Co-Authors

A. L. Kimble· 2 shared E. R. Jellison· 2 shared J. A. Hensel· 2 shared P. A. Murphy· 2 shared A. Menoret· 1 shared A. Rodriguez-Oquendo· 1 shared A. T. Vella· 1 shared B. Reese· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

A. L. Kimble

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Author profile →

2 papers

Recent·Most cited

Splice Factor Polypyrimidine tract-binding protein 1 (Ptbp1) is Required for Immune Priming of the Endothelium in Atherogenic Disturbed Flow Conditions

J. A. Hensel, S.-A. E. Nicholas, E. R. Jellison, A. L. Kimble, A. Menoret, M. Ozawa, A. Rodriguez-Oquendo, A. T. Vella, P. A. Murphy

This study identifies Ptbp1 as a critical splice factor required for endothelial priming in atherogenic disturbed flow conditions, linking its regulation of splicing and NFκB activation to vascular inflammation.

bioRxiv · Jun 18, 2021 · PreprintCell Biology

A Method for Rapid Flow-cytometric Isolation of Endothelial Nuclei and RNA from Archived Frozen Brain Tissue

A. L. Kimble, J. Silva, M. Murphy, J. A. Hensel, S.-A. E. Nicholas, E. R. Jellison, B. Reese, P. A. Murphy

This paper develops a method to isolate endothelial nuclei and RNA from archived frozen brain tissues, showing it reliably extracts endothelial RNA and correlates with whole-cell expression.

bioRxiv · May 12, 2021Cell Biology