Author

A. T. Vella

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Cell Biology· 1 Physiology· 1

Signature Assays, Organisms & Methods

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Organism:mouse· 4 Approach:experimental assay· 3 Research Focus:host-pathogen & immune response· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:development & morphogenesis· 1 Research Focus:differential expression· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

D. Yang· 2 shared E. Fikrig· 2 shared E. R. Jellison· 2 shared P. WANG· 2 shared T. Geng· 2 shared T. Lin· 2 shared A. B. Kohan· 1 shared A. G. Harrison· 1 shared

Activity by Year

2019-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 22 mutual co-author links

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2 shared papersImmunology

D. Yang

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Splice Factor Polypyrimidine tract-binding protein 1 (Ptbp1) is Required for Immune Priming of the Endothelium in Atherogenic Disturbed Flow Conditions

J. A. Hensel, S.-A. E. Nicholas, E. R. Jellison, A. L. Kimble, A. Menoret, M. Ozawa, A. Rodriguez-Oquendo, A. T. Vella, P. A. Murphy

This study identifies Ptbp1 as a critical splice factor required for endothelial priming in atherogenic disturbed flow conditions, linking its regulation of splicing and NFκB activation to vascular inflammation.

bioRxiv · Jun 18, 2021 · PreprintCell Biology

An Essential Role of UBXN3B in B Lymphopoiesis

T. Geng, D. Yang, T. Lin, A. G. Harrison, B. Wang, B. Torrance, K. Wang, Y. Wang, L. Yang, L. Haynes, G. Cheng, A. T. Vella, E. Fikrig, P. WANG

This study identifies UBXN3B's critical role in B lymphopoiesis by maintaining BLNK stability and pre-BCR signaling, leading to impaired B cell development and increased vulnerability to viral infections.

bioRxiv · Mar 4, 2021 · PreprintImmunology

STING deficiency-associated aberrant CXCL10 expression contributes to pathogenesis of arthritogenic alphaviruses

T. Lin, T. Geng, A. Harrison, D. Yang, A. T. Vella, E. Fikrig, P. Wang

This study shows that STING deficiency increases CXCL10 expression, leading to higher viral loads and inflammation in alphavirus-induced arthritis in mice.

bioRxiv · May 13, 2020 · PreprintImmunology

ApoC-III overexpression and LDLr-/- protect mice from DSS-colitis: identifying a new role for lipoprotein metabolism in Tregs

C. N. Rodia, D. Li, N. S. Tambini, Z. K. Johnson, E. R. Jellison, A. T. Vella, A. B. Kohan

This study shows that apoC-III overexpression and LDLr deficiency protect mice from DSS-colitis by increasing intestinal Tregs and IL-10, suggesting apoC-III as a potential therapeutic target for IBD.

bioRxiv · Nov 5, 2019 · PreprintPhysiology