ImmunologybioRxiv
NUDT21 links mitochondrial IPS-1 to RLR-containing stress granules and activates host antiviral defense
S. Aoyama-Ishiwatari, T. Okazaki, S.-i. Iemura…·Y. Gotoh
This study shows NUDT21 connects RLRs in stress granules to mitochondrial IPS-1, enabling antiviral defense by facilitating type I IFN induction.
DOI 10.4049/jimmunol.2000306