Author

S.-K. Guo

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Research Focus:cell signaling & trafficking· 2 Assay:cryo-EM· 1 Assay:fluorescence / live-cell microscopy· 1 Research Focus:protein folding & dynamics· 1

Frequent Co-Authors

M. E. Johnson· 3 shared A. J. Sodt· 1 shared B. Mishra· 1 shared D. Evans· 1 shared I. Saha· 1 shared S. Saffarian· 1 shared Y. Fu· 1 shared Y. Qian· 1 shared

Activity by Year

2021-2023 · peak 2/yr

Co-Author Collaboration Network

9 top collaborators · 19 mutual co-author links

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3 shared papersBiophysics

M. E. Johnson

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3 papers

Recent·Most cited

Defects in the HIV immature lattice support essential lattice remodeling within budded virions

S.-K. Guo, I. Saha, S. Saffarian, M. E. Johnson

This paper uses reaction-diffusion simulations to show that incomplete HIV immature lattice dynamics enable rapid Gag-Pol dimerization, essential for viral maturation.

eLife · Jul 12, 2023Peer-reviewedBiophysics

Temporal control by co-factors prevents kinetic trapping in retroviral Gag lattice assembly

Y. Qian, D. Evans, B. Mishra, Y. Fu, Z. Liu, S.-K. Guo, M. E. Johnson

This study uses a reaction-diffusion model to show that co-factors like IP6 delay Gag lattice assembly, preventing kinetic trapping and enabling productive lattice formation.

bioRxiv · Feb 8, 2023Biophysics

Nascent clathrin lattices spontaneously disassemble without sufficient adaptor proteins

S.-K. Guo, A. J. Sodt, M. E. Johnson

This paper quantifies the conditions necessary for stable clathrin assembly on membranes, showing that sufficient adaptor proteins are required to prevent spontaneous disassembly.

bioRxiv · Apr 19, 2021Biophysics