Author

S.-L. Hu

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Evolutionary Biology· 1 Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:non-human primate· 3 Research Focus:host-pathogen & immune response· 2 Assay:DNA methylation· 1 Organism:mouse· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

P. Polacino· 2 shared A. D. Kashuba· 1 shared A. F. Feder· 1 shared A. Misra· 1 shared B. F. Keele· 1 shared C. Kline· 1 shared C. Ma· 1 shared C.-C. Liao· 1 shared

Activity by Year

2017-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

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Curved chords = mutual co-authorship

2 shared papersMicrobiology

P. Polacino

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

In vivo serial passaging of human-simian immunodeficiency virus clones identifies viral characteristics that enhance persistent viral replication

R. Thippeshappa, P. Polacino, S. S. Chandrasekar, K. Truong, A. Misra, S.-L. Hu, D. Kaushal, J. T. Kimata

The paper identifies viral characteristics that enhance persistent replication in pigtailed macaques by serial passaging of HSIV-vif clones.

bioRxiv · Sep 15, 2021Microbiology

Vaccinia virus-based vaccines confer protective immunity against SARS-CoV-2 virus in Syrian hamsters

R. Kulkarni, W.-C. Chen, Y. Lee, C.-F. Kao, S.-L. Hu, H.-H. Ma, J.-T. Jan, C.-C. Liao, J.-J. Liang, H.-Y. Ko, C.-P. Sun, Y.-S. Lin, Y.-C. Wang, S.-C. Wei, Y.-L. Lin, , W. Chang

This study evaluates two vaccinia virus-based SARS-CoV-2 vaccines in mice and hamsters, showing they induce neutralizing antibodies and protect against infection.

bioRxiv · Aug 3, 2021Immunology

High resolution spatio-temporal assessment of simian/human immunodeficiency virus (SHIV) evolution reveals a highly dynamic process within the host

A. F. Feder, C. Kline, P. Polacino, M. Cottrell, A. D. Kashuba, B. F. Keele, S.-L. Hu, D. A. Petrov, P. Pennings, Z. Ambrose

This study tracks SHIV evolution in macaques to show drug resistance spreads rapidly across compartments but does not equilibrate, with the gut showing faster turnover and less wild-type virus retention.

bioRxiv · Jan 4, 2017Evolutionary Biology