Author

J. T. Kimata

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioengineering· 2 Microbiology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 3 Approach:experimental assay· 3 Organism:non-human primate· 3 Research Focus:host-pathogen & immune response· 2 Assay:fluorescence / live-cell microscopy· 1 Assay:imaging· 1 Approach:machine learning (classical)· 1

Frequent Co-Authors

A. Grattoni· 2 shared C. Y. X. Chua· 2 shared F. P. Pons-Faudoa· 2 shared J. E. Nichols· 2 shared K. A. Shelton· 2 shared L. R. Bushman· 2 shared P. L. Anderson· 2 shared P. N. Nehete· 2 shared

Activity by Year

2020-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBioengineering

A. Grattoni

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Ultra-long-acting refillable nanofluidic implant confers full protection against SHIV infection in non-human primates

F. P. Pons-Faudoa, N. Di Trani, S. Capuani, J. N. Campa-Carranza, B. Nehete, S. Sharma, K. A. Shelton, L. R. Bushman, F. Abdelmawla, M. Williams, L. Roon, D. Nerguizian, C. Y. X. Chua, M. M. Ittmann, J. E. Nichols, , A. Grattoni

An ultra-long-acting refillable nanofluidic implant sustained islatravir levels in non-human primates for 20 months and provided 100% protection against SHIV infection.

bioRxiv · Dec 15, 2022 · PreprintBioengineering

A Rapid, High Throughput, Viral Infectivity Assay using Automated Brightfield Microscopy with Machine Learning

R. H. Dodkins, J. R. Delaney, T. Overton, F. Scholle, A. Frias, E. Crisci, N. Huq, I. Jordan, J. T. Kimata, I. G. Goldberg

The paper introduces an automated viral infectivity assay using brightfield microscopy and machine learning, achieving rapid and accurate quantification of infection phenotypes across multiple virus types.

bioRxiv · Mar 23, 2022Microbiology

In vivo serial passaging of human-simian immunodeficiency virus clones identifies viral characteristics that enhance persistent viral replication

R. Thippeshappa, P. Polacino, S. S. Chandrasekar, K. Truong, A. Misra, S.-L. Hu, D. Kaushal, J. T. Kimata

The paper identifies viral characteristics that enhance persistent replication in pigtailed macaques by serial passaging of HSIV-vif clones.

bioRxiv · Sep 15, 2021Microbiology

Preventive efficacy of a tenofovir alafenamide fumarate nanofluidic implant in SHIV-challenged nonhuman primates

F. P. Pons-Faudoa, A. Sizovs, K. A. Shelton, Z. Momin, L. R. Bushman, J. Xu, C. Y. X. Chua, J. E. Nichols, T. Hawkins, J. F. Rooney, M. A. Marzinke, J. T. Kimata, P. L. Anderson, P. N. Nehete, R. C. Arduino, , A. Grattoni

This study evaluates a long-acting tenofovir alafenamide nanofluidic implant in nonhuman primates, showing partial protection against SHIV infection.

bioRxiv · May 13, 2020Bioengineering