GenomicsbioRxivPreprint
Single-molecule spatial genomics reveals the multi-scale organization and plasticity of extrachromosomal DNA in glioblastoma
Brett Taylor, Weixiu Dong, Tula Ann Keal…·Bogdan Bintu
This study uses single-molecule spatial genomics to show how extrachromosomal DNA is organized and regulated in glioblastoma, linking it to tumor heterogeneity and microenvironmental influences.