Weixiu Dong

This study uses single-molecule spatial genomics to show how extrachromosomal DNA is organized and regulated in glioblastoma, linking it to tumor heterogeneity and microenvironmental influences.

The paper compares cellular diversity in the primary motor cortex across human, marmoset, and mouse using single-nucleus transcriptomics and epigenomics, finding conserved cell types and species-specific adaptations.

The paper generates a multimodal cell census and atlas of the mammalian primary motor cortex, revealing a unified molecular genetic landscape and cross-species taxonomy of cell types.

This study uses single-cell RNA sequencing to analyze developing and mature glia in peripheral sensory ganglia, revealing transcriptional differences and shared molecular features across glial subtypes.

The paper uses single-cell multi-omics to analyze HARs and HGEs in fetal human brain development, identifying regulatory networks and key transcription factors involved in human-specific neurodevelopment.