Author

Clark Chen

Brown University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 2 Research Focus:clustering· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell-cell communication· 1 Research Focus:gene regulatory network inference· 1 Assay:scRNA-seq· 1

Frequent Co-Authors

Bing ReniD· 2 shared Brett TayloriD· 2 shared Lei Chang· 2 shared Timothy H. Loe· 2 shared Yang XieiD· 2 shared Zhaoning WangiD· 2 shared Abhinaba Banerjee· 1 shared Andrew M. Gardeck· 1 shared

Activity by Year

2026-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 41 mutual co-author links

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2 shared papersCancer Biology

Bing RenORCID

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Author profile →

2 papers

Recent·Most cited

Ex vivo glioblastoma migration phenotypes define clinical recurrence and tumor heterogeneity

Jay Hou, Mariah M. McMahon, Andrew Ni, Zhaoning Wang, Brett Taylor, Timothy H. Loe, Yang Xie, Lei Chang, Andrew M. Gardeck, Ziya Gokaslan, SHIRA I. DUNSIGER, Bing Ren, Clark Chen, David J. Odde

This study identifies two migratory phenotypes in glioblastoma cells ex vivo, linking them to clinical recurrence and tumor heterogeneity.

bioRxiv · Sep 2, 2026 · PreprintCancer Biology

Single-molecule spatial genomics reveals the multi-scale organization and plasticity of extrachromosomal DNA in glioblastoma

Brett Taylor, Weixiu Dong, Tula Ann Keal, Zhaoning Wang, Bharath Saravanan, Zane A. Gibbs, Yohei Miyake, Daisuke Kawauchi, Raghavendra Vadla, Abhinaba Banerjee, Omar M. Elkassih, Sahana Kashyap, B. Jones, Kseniya Malukhina, Mahsa Nafisi, , Bogdan Bintu

This study uses single-molecule spatial genomics to show how extrachromosomal DNA is organized and regulated in glioblastoma, linking it to tumor heterogeneity and microenvironmental influences.

bioRxiv · Mar 7, 2026 · PreprintGenomics