Author

Saharsh Satheesh

St. Jude Children's Research Hospital

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Alaa RefaatiD· 1 shared Anang A. ShelatiD· 1 shared Ankhbayar Lkhagva· 1 shared Anthony A. HighiD· 1 shared Chandni Karuhatty· 1 shared Elizabeth S. StewartiD· 1 shared Haiyan TaniD· 1 shared Kasturee ChakrabortyiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alaa RefaatORCID

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1 paper

Recent·Most cited

SLFN11 Loss-Induced Chemoresistance is Associated with Overexpression of Glycerophospholipid Biosynthesis in Ewing Sarcoma.

Kasturee Chakraborty, Ritambhar Burman, Saharsh Satheesh, Matthew Kieffer, Chandni Karuhatty, Zuo‐Fei Yuan, Haiyan Tan, Ankhbayar Lkhagva, Anthony A. High, Xusheng Wang, Alaa Refaat, Weixing Zhang, Yaxu Wang, Yiping Fan, M. Madan Babu, , Puneet Bagga

The paper identifies glycerophospholipid biosynthesis upregulation as a mechanism of chemoresistance in SLFN11-loss Ewing sarcoma and shows that inhibiting this pathway enhances DNA-damaging agent efficacy.

bioRxiv · May 9, 2025 · PreprintCancer Biology