Neuronal DNA repair reveals strategies to influence CRISPR editing outcomes
Gokul N. Ramadoss, Samali J. Namaganda, Manasi M. Kumar, Jennifer R. Hamilton, Rohit Kumar Sharma, Karena G. Chow, Luke A. Workley, Bria L Macklin, Mengyuan Sun, Alvin S. Ha, Jiacheng Liu, Christof Fellmann, Hannah L. Watry, Philip H. Dierks, Rudra S. Bose, , Bruce R. Conklin
The paper investigates DNA repair in postmitotic neurons and shows that manipulating repair pathways can influence CRISPR editing outcomes.
Nature Communications · Nov 17, 2025Peer-reviewedMolecular Biology