Author

Samantha Adamson DiGruccio

Washington University in St. Louis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Organism:human· 1 Organism:mouse· 1 Assay:proteomics· 1

Frequent Co-Authors

Isabella MelenaiD· 1 shared Jeong Hun Jo· 1 shared Jing W. HughesiD· 1 shared Jonathan Campbell· 1 shared Lifei ZhuiD· 1 shared Shannon E. TownsendiD· 1 shared Xinhang DongiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 21 mutual co-author links

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1 shared paperCell Biology

Isabella MelenaORCID

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1 paper

Recent·Most cited

Cell BiologyMolecular MetabolismPeer-reviewedMar 25, 2026

Primary cilia regulate GLP-1 signaling in pancreatic beta cells

Isabella Melena, Jeong Hun Jo, Shannon E. Townsend…·Jing W. Hughes

This study shows primary cilia are essential for GLP-1R signaling in pancreatic beta cells, as their loss impairs insulin secretion and cAMP/Ca2+ responses.

4 citationstop 1%

mousehuman

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