Author

Joseph C. Sanchez

University of WashingtonORCID 0000-0001-8170-4744Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Genetics· 1 Genomics· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Organism:yeast· 3 Research Focus:cell type annotation· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:variant calling· 1

Frequent Co-Authors

Bonita J. BreweriD· 3 shared Gina M. AlvinoiD· 3 shared M. K. RaghuramaniD· 3 shared Christopher R. L. LargeiD· 2 shared Elizabeth X. KwaniD· 2 shared Madison A. MilleriD· 2 shared Maitreya J. DunhamiD· 2 shared Aaron W. MilleriD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

3 shared papersGenomics

Bonita J. BrewerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

GenomicsPLoS GeneticsPeer-reviewedJan 4, 2024

Template switching between the leading and lagging strands at replication forks generates inverted copy number variants through hairpin-capped extrachromosomal DNA

Rebecca Martin, Claudia Y. Espinoza, Christopher R. L. Large…·Bonita J. Brewer

The paper identifies a replication error mechanism called ODIRA that generates inverted copy number variants through template switching at replication forks, using yeast as a model system.

14 citations

yeastexperimental assay

𝕏 PostBluesky

Molecular BiologybioRxivPreprintFeb 25, 2021

Coordination of genome replication and anaphase entry by rDNA copy number in S. cerevisiae

Elizabeth X. Kwan, Gina M. Alvino, Kelsey L. Lynch…·M. K. Raghuraman

The paper shows that reducing rDNA copy number in S. cerevisiae changes its replication timing, delays genome replication, and links rDNA to cell cycle control via Cdc14p sequestration.

2 citations

yeastexperimental assay

𝕏 PostBluesky

GeneticsGeneticsPeer-reviewedJul 10, 2019

Phenotypic and genotypic consequences of CRISPR/Cas9 editing of the replication origins in the rDNA of Saccharomyces cerevisiae

Joseph C. Sanchez, Anja R. Ollodart, Christopher R. L. Large…·Bonita J. Brewer

This study edits rDNA replication origins in yeast using CRISPR/Cas9, revealing growth and lifespan consequences of such modifications.

10 citations

yeastDNA methylation

𝕏 PostBluesky