Penetratin inhibits α-synuclein fibrillation and improves locomotor functions in mice model of Parkinsons disease
Arpit Gupta, Priyanka Singh, Arpit Mehrotra, Ankur Gautam, Kottapalli Srividya, Rajlaxmi Panigrahi, Shubham Vashishtha, Jasdeep Singh, Gagandeep Jaiswal, Krishna Upadhayay, Signe Andrea Frank, Janni Nielsen, Samir Kumar Nath, Neeraj Khatri, Daniel E. Otzen, , Deepak Sharma
This study identifies penetratin as an inhibitor of α-synuclein aggregation and shows it improves locomotor function in Parkinson's disease mouse models.
bioRxiv · Jun 24, 2022 · PreprintNeuroscience