Ashutosh Kumar

This study shows lipid droplets modulate amylin aggregation and β-cell stress by controlling its conformational changes and interaction pathways.

This study shows that amylin aggregates faster on fibrillar collagen, leading to β-cell death and dysfunction, which accelerates diabetic progression.

This study identifies penetratin as an inhibitor of α-synuclein aggregation and shows it improves locomotor function in Parkinson's disease mouse models.

This study shows that α-synuclein undergoes liquid-liquid phase separation, which transitions to solid amyloid fibrils, contributing to Parkinson's disease pathogenesis.