Single-cell long-read targeted sequencing reveals transcriptional variation in ovarian cancer
Ashley Byrne, Daniel Le, Kostianna Sereti, Hari Menon, Samir Vaidya, Neha Patel, Jessica M. Lund, Ana Xavier‐Magalhães, Minyi Shi, Yuxin Liang, Timothy Sterne-Weiler, Zora D. Modrusan, William Stephenson
This study introduces scTaILoR-seq, a long-read targeted RNA sequencing method, to enhance single-cell transcriptome analysis and identify isoform variation and SNV associations in ovarian cancer.
Nature Communications · Aug 12, 2024Peer-reviewedGenomics