Author

Samir Vaidya

GenentechORCID 0009-0001-4675-7645Unclaimed ORCID profile · follow to get notified of new preprints

Additional preprints under this name without ORCID

Samir Vaidya2 papers · Genentech

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:genetic perturbation / CRISPR· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

Alissa D. GuarnacciaiD· 1 shared Anwesha DeyiD· 1 shared Bence DánieliD· 1 shared Benjamin J. TomblingiD· 1 shared Carsten PeukertiD· 1 shared Daniel LeiD· 1 shared Gözde Ulas· 1 shared James J. CrawfordiD· 1 shared

Activity by Year

2025-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Alissa D. GuarnacciaORCID

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1 paper

Recent·Most cited

TEAD-targeting small molecules induce a cofactor switch to regulate the Hippo pathway

Alissa D. Guarnaccia, Thijs J. Hagenbeek, Wendy Lee, Noelyn M. Kljavin, Meena Choi, Benjamin J. Tombling, Carsten Peukert, Gözde Ulas, Vasumathi Kameswaran, Daniel Le, Sayantanee Paul, Samir Vaidya, Jason R. Zbieg, James J. Crawford, Bence Dániel, , Jennie Rebecca Lill

The paper identifies small molecules that induce a cofactor switch in TEAD proteins from YAP to VGLL4, repressing pro-growth gene networks and showing anti-proliferative effects.

Proceedings of the National Academy of Sciences · Jul 3, 2025Peer-reviewedCancer Biology