Antibodies blocking PlGF or VEGF interactions with the NRP1 receptormediate anti-proliferative effects
Samuel A. Blackman, Ahlam N. Qerqez, Alison G. Lee, Nicole V. Johnson, Justin M. Owens, Grace Pei‐Chun Lai, Emma C Aldrich, Kayla G. Sprenger, Jangsoon Lee, Sophie Verrier, Martin James Stoddart, Annalee W. Nguyen, Jennifer A. Maynard
The paper identifies antibodies that block PlGF or VEGFA interactions with NRP1, showing anti-proliferative effects in cancer cells and reduced angiogenesis.
Journal of Biological Chemistry · Apr 17, 2026Peer-reviewedBiochemistry