Author

Samuel A. Sakhai

University of California, San Francisco

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Neuroscience· 4

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Research Focus:differential expression· 2 Research Focus:cell type annotation· 1 Research Focus:drug response / drug discovery· 1 Assay:proteomics· 1 Organism:rat· 1 Approach:statistical model· 1

Frequent Co-Authors

Dorit Ron AiD· 4 shared Yann EhingeriD· 4 shared Jeffrey J. MoffatiD· 3 shared Khanhky Phamluong· 3 shared Anthony L. BergeriD· 1 shared David Darevesky· 1 shared Drishti SonejaiD· 1 shared Ellanor L. Whiteley· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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4 shared papersNeuroscience

Dorit Ron AORCID

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4 papers

Recent·Most cited

The BDNF Val68Met polymorphism causes a sex specific alcohol preference over social interaction and also acute tolerance to the anxiolytic effects of alcohol, a phenotype driven by malfunction of BDNF in the ventral hippocampus of male mice

Jeffrey J. Moffat, Samuel A. Sakhai, Zachary W. Hoisington, Yann Ehinger, Dorit Ron A

Psychopharmacology · Jan 9, 2023Peer-reviewedNeuroscience

BRAIN-DERIVED NEUROTROPHIC FACTOR IN AN ORBITOFRONTAL CORTICAL-DORSOLATERAL STRIATAL CIRCUIT GATES ALCOHOL CONSUMPTION

Jeffrey J. Moffat, Samuel A. Sakhai, Yann Ehinger, Khanhky Phamluong, Dorit Ron A

This study shows that BDNF in the vlOFC-DLS circuit reduces alcohol consumption in rodents, but not saccharin intake or motor cortex BDNF effects.

bioRxiv · Sep 10, 2021 · PreprintNeuroscience

cAMP-Fyn signaling in the dorsomedial striatum direct pathway drives excessive alcohol use

Yann Ehinger, Nadège Morisot, Khanhky Phamluong, Samuel A. Sakhai, Drishti Soneja, Martín F. Adrover, Veronica A. Alvarez, Dorit Ron A

This study identifies the cAMP-Fyn signaling pathway in dorsomedial striatum direct pathway neurons as a driver of excessive alcohol consumption in mice.

Neuropsychopharmacology · May 17, 2020Peer-reviewedNeuroscience

Differential Correlation of Serum BDNF and microRNA Content in Rats with Rapid or Late Onset of Heavy Alcohol Use

Yann Ehinger, Khanhky Phamluong, David Darevesky, Mélanie Welman, Jeffrey J. Moffat, Samuel A. Sakhai, Ellanor L. Whiteley, Anthony L. Berger, Sophie Laguesse, Mehdi Farokhnia, Lorenzo Leggio, Marie Lordkipanidzé, Dorit Ron A

The paper examines how heavy alcohol use affects BDNF and microRNA levels in rats, finding distinct patterns between Rapid and Late Onset drinkers.

Addiction Biology · Mar 5, 2020Peer-reviewedNeuroscience