Dorit Ron A

This study shows that BDNF in vlOFC-to-DLS neurons reduces alcohol intake by decreasing habitual seeking, but not sucrose intake.

This study shows that Rac1 activation in the dorsomedial striatum of male mice contributes to alcohol-induced structural plasticity and goal-directed learning.

This study shows that Prosapip1 in the dorsal hippocampus is essential for synaptic protein localization, long-term potentiation, and spatial memory.

The paper shows that mTORC1 activation in the nucleus accumbens of alcohol-consuming mice represses glycolysis via miR-34a-5p-mediated translation repression of Aldolase A, leading to reduced L-lactate and decreased alcohol intake.

This study investigates sex differences in mTORC1 activation and rapamycin's effect on alcohol use in male and female rodents.

This study shows that LRRK2 in D1R-expressing striatal neurons reduces alcohol drinking by modulating D1R signaling and resilience to heavy drinking.

This study maps BDNF-specific corticostriatal circuits in mice, revealing distinct projections from different cortical regions to the dorsomedial and dorsolateral striatum.

This study shows that BDNF in the vlOFC-DLS circuit reduces alcohol consumption in rodents, but not saccharin intake or motor cortex BDNF effects.

This study demonstrates that dual drug administration of RapaLink-1 and RapaBlock selectively inhibits mTORC1 in the brain while protecting it in the periphery, reducing side effects and moderating alcohol use in mice.

This study identifies the cAMP-Fyn signaling pathway in dorsomedial striatum direct pathway neurons as a driver of excessive alcohol consumption in mice.

The paper examines how heavy alcohol use affects BDNF and microRNA levels in rats, finding distinct patterns between Rapid and Late Onset drinkers.

This study shows that mTORC1 in the orbitofrontal cortex drives habitual alcohol seeking, with GluN2B recruitment during withdrawal activating mTORC1 and promoting this behavior.