Drishti Soneja

The paper shows that mTORC1 activation in the nucleus accumbens of alcohol-consuming mice represses glycolysis via miR-34a-5p-mediated translation repression of Aldolase A, leading to reduced L-lactate and decreased alcohol intake.

This study maps BDNF-specific corticostriatal circuits in mice, revealing distinct projections from different cortical regions to the dorsomedial and dorsolateral striatum.

This study demonstrates that dual drug administration of RapaLink-1 and RapaBlock selectively inhibits mTORC1 in the brain while protecting it in the periphery, reducing side effects and moderating alcohol use in mice.

This study identifies the cAMP-Fyn signaling pathway in dorsomedial striatum direct pathway neurons as a driver of excessive alcohol consumption in mice.

The paper validates a native plasmid-encoded mercury resistance operon in groundwater bacteria and identifies strains capable of natural transformation.