Author

Samuel N Lee

University of Leicester

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Molecular Biology· 1

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Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

David M English· 1 shared India M BakeriD· 1 shared Khadija A Sabat· 1 shared Mark O. CollinsiD· 1 shared Shaun M. CowleyiD· 1 shared Trong Khoa PhamiD· 1 shared

Activity by Year

2024-2024 · peak 1/yr

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1 shared paperMolecular Biology

David M English

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1 paper

Recent·Most cited

Rapid degradation of Histone Deacetylase 1 (HDAC1) reveals essential roles in both gene repression and active transcription

David M English, Samuel N Lee, Khadija A Sabat, India M Baker, Trong Khoa Pham, Mark O. Collins, Shaun M. Cowley

This study rapidly degrades HDAC1 in ESCs to show its dual role in gene repression and active transcription by modulating histone acetylation at promoters and enhancers.

Nucleic Acids Research · Nov 27, 2024Peer-reviewedMolecular Biology