Author

David M English

University of Leicester

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Molecular Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Mark O. CollinsiD· 2 shared Shaun M. CowleyiD· 2 shared Ahmad Alshehri· 1 shared India M BakeriD· 1 shared India-May Baker· 1 shared John W. R. SchwabeiD· 1 shared Khadija A Sabat· 1 shared Louise FairalliD· 1 shared

Activity by Year

2024-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersMolecular Biology

Mark O. CollinsORCID

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Mutations on the surface of HDAC1 reveal molecular determinants of specific complex assembly and their requirement for gene regulation

Ahmad Alshehri, India-May Baker, David M English, Louise Fairall, Mark O. Collins, John W. R. Schwabe, Shaun M. Cowley

The paper identifies molecular determinants of HDAC1 complex assembly through mutations, showing that specific residues are critical for complex binding and gene regulation.

Nucleic Acids Research · Sep 5, 2025Peer-reviewedMolecular Biology

Rapid degradation of Histone Deacetylase 1 (HDAC1) reveals essential roles in both gene repression and active transcription

David M English, Samuel N Lee, Khadija A Sabat, India M Baker, Trong Khoa Pham, Mark O. Collins, Shaun M. Cowley

This study rapidly degrades HDAC1 in ESCs to show its dual role in gene repression and active transcription by modulating histone acetylation at promoters and enhancers.

Nucleic Acids Research · Nov 27, 2024Peer-reviewedMolecular Biology