Trong Khoa Pham

Repurposing clofarabine against enteric pathogens via metabolic starvation

This study identifies clofarabine as an inhibitor of EPEC pathogenesis by targeting bacterial and host translation, revealing a bacterial mechanism to counteract its effects.

Extracellular matrix properties and dynamics are important for butterfly scale nanostructure development

The paper investigates genes involved in extracellular matrix development in butterfly scales using RNA-seq and proteomics, identifying key genes affecting scale morphology and structure.

Glutathione Oxidation in Cerebrospinal Fluid as a Biomarker of Oxidative Stress in Amyotrophic Lateral Sclerosis

This study measures glutathione oxidation in cerebrospinal fluid of ALS patients and healthy controls, finding elevated levels and correlations with disease progression and protein oxidation.

Proteomic characterisation of Japanese quails unique seminal foam

This paper identifies 224 proteins in Japanese quail seminal foam using proteomics, revealing roles in sperm function, immune protection, and fertilization success.

Rapid degradation of Histone Deacetylase 1 (HDAC1) reveals essential roles in both gene repression and active transcription

This study rapidly degrades HDAC1 in ESCs to show its dual role in gene repression and active transcription by modulating histone acetylation at promoters and enhancers.