Author

Samuel Perreault

Pennsylvania State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

Edwin AntonyiD· 2 shared Mark HedgliniD· 2 shared Ayush MistryiD· 1 shared Grace Young· 1 shared Jessica L. Norris· 1 shared Kara G Pytko· 1 shared Lindsey O. Rogers· 1 shared Rachel L. Dannenberg· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

9 top collaborators · 30 mutual co-author links

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2 shared papersBiochemistry

Edwin AntonyORCID

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2 papers

Recent·Most cited

A novel mechanism of ubiquitin-charging a bivalent E2:RING E3 complex

Samuel Perreault, Ayush Mistry, Edwin Antony, Mark Hedglin

This study identifies a novel mechanism by which a bivalent E2:RING E3 complex facilitates E2 charging through competitive inhibition and accelerated release of charged E2.

bioRxiv · Sep 9, 2026 · PreprintBiochemistry

PCNA encircling primer/template junctions is eliminated by exchange of RPA for Rad51: Implications for the interplay between human DNA damage tolerance pathways

Jessica L. Norris, Lindsey O. Rogers, Grace Young, Kara G Pytko, Rachel L. Dannenberg, Samuel Perreault, Vikas Kaushik, Edwin Antony, Mark Hedglin

This study investigates the interplay between DNA damage tolerance pathways by comparing PCNA occupancy and RPA/Rad51 exchange at stalled replication sites.

Nucleic Acids Research · Dec 17, 2025Peer-reviewedBiophysics