Author

Grace Young

Pennsylvania State University

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Biophysics· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Organism:human· 2 Research Focus:chromatin & epigenetic regulation· 1 Assay:cryo-EM· 1 Approach:experimental assay· 1 Approach:microscopy & imaging analysis· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Mark HedgliniD· 2 shared Alfredo De BiasioiD· 1 shared Amani M. Al-AmodiiD· 1 shared Ammar Usman DanazumiiD· 1 shared Christos G. SavvaiD· 1 shared Edwin AntonyiD· 1 shared Giuseppina R. BriolaiD· 1 shared Jessica L. Norris· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersBiochemistry

Mark HedglinORCID

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Author profile →

2 papers

Recent·Most cited

Structure of the human CTF18-RFC clamp loader bound to PCNA

Giuseppina R. Briola, Muhammad Tehseen, Amani M. Al-Amodi, Grace Young, Ammar Usman Danazumi, Phong Quoc Nguyen, Christos G. Savva, Mark Hedglin, Samir M. Hamdan, Alfredo De Biasio

This study presents a cryo-EM structure of the human CTF18-RFC complex bound to PCNA, revealing structural features important for PCNA loading and Pol ε-mediated leading strand synthesis.

eLife · Feb 23, 2026Peer-reviewedBiochemistry

PCNA encircling primer/template junctions is eliminated by exchange of RPA for Rad51: Implications for the interplay between human DNA damage tolerance pathways

Jessica L. Norris, Lindsey O. Rogers, Grace Young, Kara G Pytko, Rachel L. Dannenberg, Samuel Perreault, Vikas Kaushik, Edwin Antony, Mark Hedglin

This study investigates the interplay between DNA damage tolerance pathways by comparing PCNA occupancy and RPA/Rad51 exchange at stalled replication sites.

Nucleic Acids Research · Dec 17, 2025Peer-reviewedBiophysics