A functional overlap between actively transcribed genes and chromatin boundary elements
Caroline L. Harrold, Matthew E. Gosden, Lars L P Hanssen, Rosa J. Stolper, Damien J. Downes, Jelena M. Telenius, Daniel Biggs, Chris Preece, Samy Alghadban, Jacqueline A. Sharpe, Benjamin Davies, Jacqueline A. Sloane-Stanley, Mira T. Kassouf, Jim R. Hughes, Douglas R. Higgs
The paper shows that actively transcribed genes can function as chromatin boundary elements, similar to CTCF-bound sites, by stalling chromatin loop extrusion.
bioRxiv · Jul 1, 2020 · PreprintGenomics