Author

Sanaz Sabzehei

Universidade de Santiago de Compostela

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:protein folding & dynamics· 1 Assay:protein structure· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Arcadio GuerraiD· 2 shared Hasier ErañaiD· 2 shared Human RezaeiiD· 2 shared Iria Díaz-AriasiD· 2 shared Joaquı́n CastillaiD· 2 shared Manuel Martín‐PastoriD· 2 shared Víctor M. Sánchez‐PedregaliD· 2 shared Emiliano BiasiniiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 43 mutual co-author links

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2 shared papersBiochemistry

Arcadio GuerraORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Unfolding of the disease-linked bank vole prion protein E200K in the context of PrPSc propagation

Sanaz Sabzehei, Hasier Eraña, Iria Díaz-Arias, Raúl Cacheiro, Arcadio Guerra, Sara María Alvarez-Cardama, Yaiza de León-Vega, Human Rezaei, Joaquı́n Castilla, Víctor M. Sánchez‐Pedregal, Jesús R. Requena, Manuel Martín‐Pastor

This study investigates the early unfolding events of the E200K mutant prion protein in bank voles, comparing it to the wild-type protein to understand its enhanced capacity to generate PrPSc.

bioRxiv · Oct 14, 2026 · PreprintBiochemistry

Unfold to refold: Tracking the initial steps of PrPC unfolding in the context of PrPSc propagation

Sanaz Sabzehei, Marta Rigoli, Raul Cacheiro, Iria Díaz-Arias, Hasier Eraña, Rubén P. Lago, Arcadio Guerra, Human Rezaei, Joaquı́n Castilla, Emiliano Biasini, Víctor M. Sánchez‐Pedregal, Manuel Martín‐Pastor, Jesus R. Requenaa

The paper investigates the early steps of PrPC unfolding during PrPSc propagation using NMR and simulations, identifying key regions and mechanisms of unfolding/refolding.

bioRxiv · Oct 11, 2025 · PreprintBiochemistry