Cruciform-forming AT/TA repeats are acted upon by structure selective endonucleases and Rad51 prior to repositioning to the nuclear periphery for repair
Jan Leendert Boer, Sara Crippen, A. C. Kim, Daphne N. Kramer, Bertrand Theulot, Daniel Dovrat, Amir Aharoni, Duncan J. Smith, Catherine H. Freudenreich
The paper shows that AT/TA repeats form DNA structures that are processed by nucleases and repositioned to the nuclear periphery for repair.
Nucleic Acids Research · Feb 24, 2026Peer-reviewedGenetics