Amir Aharoni

This study develops a bispecific antibody that enhances T-cell engagement with AXL+ cells, improving anti-PD-1 therapy efficacy in HNSCC by remodeling the tumor microenvironment.

The paper shows that AT/TA repeats form DNA structures that are processed by nucleases and repositioned to the nuclear periphery for repair.

This study shows that replisome progression through R-loops reverses transcriptional repression and prevents fork stalling by reducing RNAPII density.

The paper creates a proteome-wide yeast library with HA tags to study protein function, size, abundance, and localization.