Bertrand Theulot

Genome-wide mapping of helicase-generated ssDNA reveals Hrq1 activity at RNA polymerase III-transcribed genes

The paper maps helicase activity genome-wide using AID-mediated mutational footprints, revealing Hrq1's association with RNA polymerase III-transcribed genes.

A Closed-Form Bayesian Model for DNA Replication Reveals Intrinsic Origin Timing and Activation Delays

This paper introduces a Bayesian model for DNA replication that infers origin timing and activation delays using RFD data, revealing 150 origins with significant delays in yeast.

Cruciform-forming AT/TA repeats are acted upon by structure selective endonucleases and Rad51 prior to repositioning to the nuclear periphery for repair

The paper shows that AT/TA repeats form DNA structures that are processed by nucleases and repositioned to the nuclear periphery for repair.

Nanotiming: telomere-to-telomere DNA replication timing profiling by nanopore sequencing

Nanotiming provides high-resolution telomere-to-telomere replication timing profiles using nanopore sequencing, validated in yeast with cost and simplicity advantages.

FORK-seq: replication landscape of the Saccharomyces cerevisiae genome by nanopore sequencing

FORK-seq maps DNA replication at single-molecule resolution in yeast, revealing previously missed initiation and termination events.