Antibiotic perturbation of the human gut phageome preserves its individuality and promotes blooms of virulent phages.
Eugen Pfeifer, Camille d’Humières, Quentin Lamy-Besnier, Florian Plaza Oñate, Rémi Denise, Sara Dion, Bénédicte Condamine, Marie Touchon, Laurence Ma, Charles Burdet, France Mentré, Érick Denamur, Eduardo P. C. Rocha, the PrediRes study group
This study examines how antibiotic treatment affects the gut phageome, finding reduced diversity and increased virulent phage blooms, which may help restore bacterial diversity through kill-the-winner dynamics.
Cell Reports · Jul 21, 2025Peer-reviewedMicrobiology