Quentin Lamy-Besnier

Gnotobiotic OMM12 mice support sustained Clostridioides difficile colonization without antibiotic pretreatment

This study shows that gnotobiotic OMM12 mice can sustain Clostridioides difficile colonization for 20 days without antibiotic pretreatment, allowing research on host-microbiota-pathogen interactions.

Differential translocation of bacteriophages across the intestinal barrier in health and Crohn's disease

The paper investigates phage translocation across the intestinal barrier in health and Crohn's disease, finding increased phage presence in blood samples from CD patients.

Bacteriophage PAK_P3 genome structuration and dynamics during infection of Pseudomonas aeruginosa reveal specific interactions patterns

The paper investigates the 3D genome structuration and dynamics of bacteriophage PAK_P3 during infection of Pseudomonas aeruginosa, revealing specific interactions between phage and host genomes.

Antibiotic perturbation of the human gut phageome preserves its individuality and promotes blooms of virulent phages.

This study examines how antibiotic treatment affects the gut phageome, finding reduced diversity and increased virulent phage blooms, which may help restore bacterial diversity through kill-the-winner dynamics.

T7 DNA polymerase treatment improves quantitative sequencing of both double-stranded and single-stranded DNA viruses

The paper compares DNA preparation methods for virome sequencing, finding that T7 DNA polymerase treatment improves representation of both ssDNA and dsDNA viruses compared to MDA or xGen kit.

The human blood harbors a phageome which differs in Crohn's disease

The paper studies the blood virome in healthy individuals and Crohn's disease patients, finding distinct viral communities associated with the disease.