Laurence Ma

This paper presents a targeted amplicon sequencing panel for cost-effective high-throughput genotyping of Aedes aegypti, showing it can replicate WGS population structure analyses and accurately measure genetic admixture.

The paper investigates viral-host lineage stability and mobile element diversity in a marine community, finding that ecological constraints promote long-term stability and diversity of phages and mobile genetic elements.

This study sequences and analyzes genetic diversity in SGG isolates associated with colorectal cancer, revealing no specific pathogenicity island and highlighting surface proteins and other factors involved in host colonization.

This study examines how antibiotic treatment affects the gut phageome, finding reduced diversity and increased virulent phage blooms, which may help restore bacterial diversity through kill-the-winner dynamics.

This study uses TALENs to contract CTG repeats in DM1 cells, achieving 68% contraction with a recoded TALEN, while SaCas9 failed, and identifies potential off-target effects.

The paper generates an ORFeome collection and associated tools for studying Candida albicans pathogenesis.

The paper compares the midgut bacterial microbiome of geographically diverse Aedes aegypti colonies reared in the same insectary, finding they are similar, suggesting microbiota is environmentally determined.