The small MAF transcription factor MAFG co-opts MITF to promote melanoma progression
Olga Vera, Michael Martinez, Zulaida Soto-Vargas, Kaizhen Wang, Xiaonan Xu, Nicol Mecozzi, Harini Murikipudi, Sara Ruiz-Buceta, Manon Chadourne, Benjamin Posorske, Ariana M. Angarita, Ilah Bok, Juan D. Ulloa Arrieta, Qian Liu, Yumi Kim, , Florian A. Karreth
This study identifies MAFG as a driver of melanoma progression by interacting with MITF to alter gene expression and promote a dedifferentiated melanoma phenotype.
Nature Communications · May 21, 2026Peer-reviewedCancer Biology