Author
University of South FloridaORCID 0000-0001-6033-7041Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Nicol Mecozzi, Olga Vera, Kelly M. Guzman…·Florian A. Karreth
This study identifies circPMS1 as a pro-metastatic circRNA in melanoma that promotes cytoskeletal remodeling and metastasis by scaffolding LIM proteins.
Olga Vera, Michael Martinez, Zulaida Soto-Vargas…·Florian A. Karreth
This study identifies MAFG as a driver of melanoma progression by interacting with MITF to alter gene expression and promote a dedifferentiated melanoma phenotype.
Xiaonan Xu, Vinesh Jarajapu, Manon Chadourne…·Florian A. Karreth
This study identifies FRA1 as a driver of melanoma metastasis and shows that targeting its downstream genes AXL, CDK6, and FSCN1 suppresses metastasis and improves survival.
Manon Chadourne, Crystal Griffith, Neel Jasani…·Florian A. Karreth
Neel Jasani, Xiaonan Xu, Benjamin Posorske…·Florian A. Karreth
This study identifies PHGDH induction via MAPK and mTORC1 pathways as essential for melanoma formation and shows that combining BRAFV600E inhibition with serine restriction can target this vulnerability.