Author

Sarah Bui

University of Pennsylvania

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Molecular Biology· 3 Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:mouse· 4 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:statistical model· 2

Frequent Co-Authors

Aditi MurthyiD· 4 shared L. Raposo RodrígueziD· 4 shared Michael Francis BeersiD· 4 shared Yaniv TomeriD· 4 shared Charlotte H Cooper· 3 shared Jeremy B. KatzeniD· 3 shared Swati IyeriD· 3 shared Willy Roque Barboza· 3 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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4 shared papersMolecular Biology

Aditi MurthyORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Inflammatory Fibroblasts Promote Repair After Injury Through Epithelial Proliferation

L. Raposo Rodríguez, Willy Roque Barboza, Aditi Murthy, Niran Hadad, Sarah Bui, Dakota L Jones, Yaniv Tomer, Charlotte H Cooper, Anamarie Reineberg, Rea Chroneos, Evan T. Hoffman, Surafel Mulugeta, Jeremy B. Katzen, Jonathan A. Kropski, Nicholas E. Banovich, Michael Francis Beers

The paper identifies inflammatory fibroblasts that promote lung repair by enhancing epithelial proliferation through BMP signaling, validated across multiple models and human disease.

bioRxiv · Aug 4, 2026 · PreprintMolecular Biology

Divergent Pathways of Surfactant Protein C Maturation for Disease-Associated Isoforms

Sarah Bui, Anamarie Reineberg, Dakota L. Jones, Cheng-Lun Na, Joseph Kitzmiller, Luis R Rodriguez, Aditi Murthy, Swati Iyer, Charlotte Cooper, Rea Chroneos, Yaniv Tomer, Surafel Mulugeta, Timothy E. Weaver, Darrell N. Kotton, Konstantinos–Dionysios Alysandratos, , Michael Francis Beers

This study compares the maturation pathways of wild-type and disease-associated SP-C mutants, showing divergent trafficking and processing due to mutations.

Journal of Biological Chemistry · Feb 5, 2026Peer-reviewedCell Biology

REGULATORY T CELLS PROTECT AGAINST ABERRANT REMODELING IN A MOUSE MODEL OF PULMONARY FIBROSIS

Aditi Murthy, Luis R Rodriguez, Willy Roque Barboza, Yaniv Tomer, Sarah Bui, Paige Carson, Thalia T. Dimopoulos, Swati Iyer, Katrina Chavez, Charlotte H Cooper, Jeremy B. Katzen, Michael Francis Beers

This study shows that regulatory T cells (Tregs) protect against pulmonary fibrosis in a mouse model by reducing fibrosis and promoting tissue repair through immune-mesenchymal-epithelial signaling.

Mucosal Immunology · Dec 27, 2025Peer-reviewedMolecular Biology

Impaired AMPK Control of Alveolar Epithelial Cell Metabolism Promotes Pulmonary Fibrosis

L. Raposo Rodríguez, Konstantinos–Dionysios Alysandratos, Jeremy B. Katzen, Aditi Murthy, Willy Roque Barboza, Yaniv Tomer, Sarah Bui, Rebeca Acín Perez, Anton Petcherski, Kasey Minakin, Paige Carson, Swati Iyer, Katrina Chavez, Charlotte H Cooper, Apoorva Babu, , Michael Francis Beers

The paper identifies impaired AMPK signaling in AT2 cells as a driver of pulmonary fibrosis and shows restoring AMPK alleviates fibrosis in vivo.

JCI Insight · Jul 1, 2025Peer-reviewedMolecular Biology

GRASP55 Regulates Sorting and Maturation of the Lysosomal Enzyme β-Hexosaminidase A

Sarah Reem Akaaboune, Aadil Javed, Sarah Bui, Alissa Wierenga, Yanzhuang Wang

This study shows GRASP55 regulates lysosomal enzyme trafficking by affecting HEXA sorting, M6P receptor interaction, and GNPTAB expression, leading to altered enzyme maturation and secretion.

Molecular Biology of the Cell · Jan 22, 2025Peer-reviewedCell Biology