Apoorva Babu

The paper identifies impaired AMPK signaling in AT2 cells as a driver of pulmonary fibrosis and shows restoring AMPK alleviates fibrosis in vivo.

This study maps the temporal sequence of mouse lung regeneration after viral injury, identifying persistent injury-associated cell states and their role in alveolar niche repair.

This study identifies aberrant transitional alveolar epithelial cells in a mouse fibrosis model and shows they activate fibroblasts through a profibrotic secretome.

The paper generates gene expression data from iPSC-derived cardiomyocytes in a multiethnic cohort and makes the results publicly available.

This study shows that disrupting PGF2α receptor signaling reduces fibrosis in a mouse model of IPF by altering fibroblast dynamics and reducing fibrotic endpoints.

The paper constructs a single-cell reference atlas for human and mouse lung tissues to improve cell type annotation and data integration.