Cis-regulatory elements driving motor neuron-restricted viral payload expression within the mammalian spinal cord
M. Aurel Nagy, Spencer Price, Kristina Wang, Stanley Gill, Erika Ren, Lorna McElrath, Victoria Pajak, Sarah Deighan, Bin Liu, Xiaodong Liu, Aissatou Diallo, Shih‐Ching Lo, Robin J. Kleiman, Christopher E. Henderson, Junghae Suh, , Siniša Hrvatin
This study identifies cis-regulatory elements that drive motor neuron-specific gene expression in viral vectors, showing selectivity in mice and non-human primates.
bioRxiv · Sep 2, 2024 · PreprintNeuroscience