Xiaodong Liu

This study shows neurogranin binds to the L-type Ca2+ channel, facilitates calmodulin delivery, and enhances channel function through dynamic interactions.

This paper develops a method to inhibit L-type CaV1 channels in neurons using opto-chemogenetic tools, showing acute and potent inhibition through membrane-assisted molecular linkage.

This study identifies cis-regulatory elements that drive motor neuron-specific gene expression in viral vectors, showing selectivity in mice and non-human primates.

This study compares GCaMP-X and GCaMP for long-term Ca2+ imaging in neurons, finding GCaMP-X provides better long-term expression and less cytotoxicity.

The paper identifies opposing transcription signals mediated by CaV1-encoded DCT peptides and shows they are regulated by C-terminus mediated inhibition.