Author

Christopher E. Henderson

Biogen (United States)ORCID 0000-0002-9936-3279Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Organism:mouse· 3 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Research Focus:drug response / drug discovery· 1 Research Focus:gene regulatory network inference· 1 Research Focus:perturbation response prediction· 1 Approach:statistical model· 1

Frequent Co-Authors

Aissatou Diallo· 1 shared Angelita Alcos· 1 shared Bin LiuiD· 1 shared Daniel Martin WattersoniD· 1 shared Eileen Workman· 1 shared Eric C. GriffithiD· 1 shared Erika ReniD· 1 shared Ivan TattoliiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 16 mutual co-author links

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Curved chords = mutual co-authorship

1 shared paperNeuroscience

Aissatou Diallo

Mutual co-authors in cluster

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3 papers

Recent·Most cited

A chemical screen identifies p38 MAPK inhibition as a candidate neuroprotective strategy for combinatorial SMA therapy

Maria Jose Carlini, Jorge Espinoza‐Derout, Meaghan Van Alstyne, Sarah Tisdale, Eileen Workman, Marina K Triplett, Ivan Tattoli, Shubhi Yadav, Christopher E. Henderson, Daniel Martin Watterson, Livio Pellizzoni

This study identifies p38 MAPK inhibition as a neuroprotective strategy that synergizes with SMN upregulation to improve motor function and survival in SMA mice.

bioRxiv · Mar 6, 2025 · PreprintNeuroscience

Cis-regulatory elements driving motor neuron-restricted viral payload expression within the mammalian spinal cord

M. Aurel Nagy, Spencer Price, Kristina Wang, Stanley Gill, Erika Ren, Lorna McElrath, Victoria Pajak, Sarah Deighan, Bin Liu, Xiaodong Liu, Aissatou Diallo, Shih‐Ching Lo, Robin J. Kleiman, Christopher E. Henderson, Junghae Suh, , Siniša Hrvatin

This study identifies cis-regulatory elements that drive motor neuron-specific gene expression in viral vectors, showing selectivity in mice and non-human primates.

bioRxiv · Sep 2, 2024 · PreprintNeuroscience

Elimination of glutamatergic transmission from Hb9 interneurons does not impact treadmill locomotion

Lina M. Koronfel, Kevin C. Kanning, Angelita Alcos, Christopher E. Henderson, Robert M. Brownstone

This study shows that eliminating glutamatergic transmission from Hb9 interneurons does not impair treadmill locomotion, suggesting these neurons are not essential for locomotor rhythmogenesis.

Scientific Reports · Aug 6, 2021Peer-reviewedNeuroscience