N-terminal truncation diversifies USP18 function during early myogenesis
Tom I. Nijssen, Simeon D. Draganov, Milad Shademan, Sarah Flannery, Iolanda Vendrell, Benedikt Mathias Kessler, Adán Pinto-Fernández, Vered Raz
This study shows that the N-terminal truncation of USP18 generates a short isoform (SF) with distinct functions in muscle differentiation compared to the long isoform (LF).
bioRxiv · Oct 18, 2026 · PreprintCell Biology