Simeon D. Draganov

This study shows that the N-terminal truncation of USP18 generates a short isoform (SF) with distinct functions in muscle differentiation compared to the long isoform (LF).

This study identifies USP24 as a novel ISG15 cross-reactive deubiquitinase that de-ISGylates MOV10 to negatively regulate IFN-I production.

This paper introduces a high-throughput activity proteomics pipeline for discovering deubiquitinase inhibitors, identifying potent and selective inhibitors with minimal optimization.

The paper introduces a chemical tool, 6Yn-Pro, for identifying intracellular ADP-ribosylated proteins through metabolic labeling and chemical proteomics in HEK293T cells.