Author

Sarah Lin

Princeton University

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Neuroscience· 1

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Assay:bulk RNA-seq· 1 Organism:C. elegans· 1 Research Focus:differential expression· 1 Approach:statistical model· 1

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Coleen Tara MurphyiD· 1 shared Katherine S. MorilloiD· 1 shared Rachel L. KaletskyiD· 1 shared Shiyi ZhouiD· 1 shared Yifei WengiD· 1 shared

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2024-2024 · peak 1/yr

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1 shared paperNeuroscience

Coleen Tara MurphyORCID

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1 paper

Recent·Most cited

The Neuron-specific IIS/FOXO Transcriptome in Aged Animals Reveals Regulatory Mechanisms of Neuronal and Cognitive Aging

Yifei Weng, Shiyi Zhou, Katherine S. Morillo, Rachel L. Kaletsky, Sarah Lin, Coleen Tara Murphy

This study investigates the IIS/FOXO pathway's role in cognitive aging using C. elegans, finding that daf-2 mutants exhibit distinct transcriptomic changes that enhance neuronal resilience.

eLife · Apr 8, 2024Peer-reviewedNeuroscience