Sarah Tarhini

Virus-against-virus dominant-negative interference strategy targeting a viral CC chemokine prevents cytomegalovirus-related neurodevelopmental pathogenesis

This study shows that a dominant-negative mutant of the viral chemokine RCK3 prevents CMV-induced neurodevelopmental disorders in a rat model.

Pathogenic MTOR somatic variant causing focal cortical dysplasia drives hyperexcitability via overactivation of neuronal GluN2C NMDA receptors

This study shows that a somatic MTOR variant in FCD type II causes hyperexcitability through overactivation of GluN2C NMDA receptors in rat neurons.