Mitochondrial perturbation adapts the proteome from early to advanced immune responses
Jessica Alvarez, Sofia Rivera, Sarahbeth Roberts, Natalia E Herrera, Tyron Chang, Krishna Kanth Chitta, Jeon Lee, Andrew S. Lemoff, Dustin C. Hancks
The paper shows mitochondrial state influences protein-level immune responses, with OXPHOS supporting early immune proteins and mitochondrial perturbation favoring inflammatory mediators in mice.
bioRxiv · Sep 14, 2026 · PreprintImmunology