Dual Histone Methyl Reader ZCWPW1 Facilitates Repair of Meiotic Double Strand Breaks
Mohamed Mahgoub, Jacob Paiano, Melania Bruno, Wei Wu, Sarath Pathuri, Xing Zhang, Sherry Ralls, Xiaodong Cheng, André Nussenzweig, Todd S. Macfarlan
This study identifies ZCWPW1 as a dual histone methylation reader essential for meiotic DSB repair in vertebrates, showing its co-expression and co-evolution with PRDM9.
eLife · Apr 30, 2020Peer-reviewedGenetics