Author

Mohamed Mahgoub

National Institutes of HealthORCID 0000-0003-2687-7874Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:DNA methylation· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Approach:statistical model· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:variant calling· 1

Frequent Co-Authors

André NussenzweigiD· 1 shared Brittany Johnson· 1 shared Catrina C. FronickiD· 1 shared Christopher Markovic· 1 shared David H. SpenceriD· 1 shared Emilee N. KotnikiD· 1 shared Haley AbeliD· 1 shared Heidi Struthers· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperGenetics

André NussenzweigORCID

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2 papers

Recent·Most cited

GenomicsbioRxivPreprintSep 18, 2025

Intermediately Methylated Regions in Normal Cells Are Epimutation Hotspots in Cancer

Mohamed Mahgoub, Haley Abel, Nidhi Davarapalli…·David H. Spencer

The paper identifies intermediate methylation regions in normal cells as epimutation hotspots in cancer, showing they are prone to clonal epimutations in leukemia and other cancers.

DOI 10.1101/2025.09.18.677221

humanDNA methylation

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GeneticseLifePeer-reviewedApr 30, 2020

Dual Histone Methyl Reader ZCWPW1 Facilitates Repair of Meiotic Double Strand Breaks

Mohamed Mahgoub, Jacob Paiano, Melania Bruno…·Todd S. Macfarlan

This study identifies ZCWPW1 as a dual histone methylation reader essential for meiotic DSB repair in vertebrates, showing its co-expression and co-evolution with PRDM9.

47 citations

mousehuman

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