Cancer BiologyLeukemiaPeer-reviewed
The neuronal homeobox transcription factor HMX3 is a crucial vulnerability factor in MECOM-negative KMT2A::MLLT3 acute myelomonocytic leukemia
Saioa Arza-Apalategi, Branco M. H. Heuts, Saskia M. Bergevoet…·Bert A. van der Reijden
The paper identifies HMX3 as a critical vulnerability in MECOM-negative KMT2A::MLLT3 AML, showing it promotes proliferation and blocks differentiation.
4 citations